Sorry, you need to enable JavaScript to visit this website.

The Two-Faced Potato Virus X: From Plant Pathogen to Smart Nanoparticle

TitleThe Two-Faced Potato Virus X: From Plant Pathogen to Smart Nanoparticle
Publication TypeArticolo su Rivista peer-reviewed
Year of Publication2015
AuthorsLico, Chiara, Benvenuto Eugenio, and Baschieri Selene
JournalFrontiers in Plant Science
Volume6:1009
Date Published17 November 2015
ISSN1664462X
Abstract

Potato virus X (PVX) is a single-stranded RNA plant virus, historically investigated in light of the detrimental effects on potato, the world’s fourth most important food commodity. The study of the interactions with cells, and more generally with the plant, both locally and systemically, significantly contributed to unveil the mechanisms underlying gene silencing, fundamental not only in plant virology but also in the study of gene expression regulation. Unraveling the molecular events of PVX infection paved the way for the development of different viral expression vectors and consequential applications in functional genomics and in the biosynthesis of heterologous proteins in plants. Apart from that, the ease of manipulation and the knowledge of the virus structure (particle dimensions, shape and physicochemical features) are inspiring novel applications, mainly focused on nanobiotechnology. This review will lead the reader in this area, spanning from fundamental to applied research, embracing fields from plant pathology to vaccine and drug-targeted delivery, imaging and material sciences. Due to the versatile moods, PVX holds promise to become an interesting nanomaterial, in view to create the widest possible arsenal of new “bio-inspired” devices to face evolving issues in biomedicine and beyond. © 2015 Lico, Benvenuto and Baschieri.

Notes

cited By 3

URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-84947611181&doi=10.3389%2ffpls.2015.01009&partnerID=40&md5=89059dce01f05e4ae52fe56c2bc35205
DOI10.3389/fpls.2015.01009
Citation Key5473