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Chemical characterization of Narcissus poeticus from sirente-velino (apennines-Italy): Galantamine accumulation and distribution of allergenic compounds in the flower

TitoloChemical characterization of Narcissus poeticus from sirente-velino (apennines-Italy): Galantamine accumulation and distribution of allergenic compounds in the flower
Tipo di pubblicazioneArticolo su Rivista peer-reviewed
Anno di Pubblicazione2017
AutoriFerri, D., Ubaldi Carla, Marcozzi G., Fasciani P., Bacchetta Loretta, and Pace L.
RivistaNatural Product Communications
Volume12
Paginazione15-18
ISSN1934578X
Parole chiavealkaloid, allergen, article, bioaccumulation, Chemical analysis, Chemical composition, concentration (parameters), controlled study, dry weight, flower, galantamine, in vitro propagation, Italy, Narcissus, Narcissus poeticus, Narcissus poeticus extract, nonhuman, plant bulb, Plant extract, plant root, plant stem, plant yield, solvent, trend study, unclassified drug
Abstract

Species of Narcissus (family Amaryllidaceae) are a potential source for large-scale extraction of alkaloids and fragrances. The bulbs typically accumulate a large number of alkaloids, including galantamine, a benzazepine alkaloid proven to be a cholinesterase inhibitor and which is used in the treatment of Alzheimer's disease. The presence of galantamine in N. poeticus L. collected in Abruzzo (Italy) was assessed and several levels of alkaloid were found in all parts of the plant (flower, stem, bulb and root) and not only in the bulb. The amount of galantamine obtained was tested by using two different extraction solvents. Extraction of N. poeticus absolute from the flowers was also performed, as this product is an important floral note in perfumery, and the distribution of allergenic compounds in the coronas and in the tepals was assessed. Moreover, the in vitro propagation of N. poeticus was tested as it may be a valuable resource from which to produce biomolecules, as an alternative to chemical synthetic processes.

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URLhttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85019158105&partnerID=40&md5=08786f5e882c493e8db7a293cde32d36
DOI10.1177/1934578x1701200105
Citation KeyFerri201715